Genetically Modified Cell Lines / Isogenic Cell Lines

 

Isogenic cell lines 可用於細胞生物學研究,例如 genotype 對 cellular phenotype 的影響以及用於平行、高通量篩選具有 genotype-specific 毒性的治療化合物。Isogenic cell lines 是通過導入 targeted gene 突變從 parental line 改造而來的 cell line。 parental cell line 可當作對照細胞株。

 

產品包含

Neuronal Disease Specific Isogenic Knockout iPSCs

hiPSC 為生理相關的細胞株,可用於巴金森氏病 (Parkinson's disease)、阿爾茨海默氏病、ALS、精神分裂症和自閉症研究。

 

Reporter iPSC Lines (Isogenic)

Reporter gene iPSC lines 是定量研究複雜的遺傳和分子機制的理想工具

 

Catalog ID# Product Name Size
ASE-9211  iPS Cells (iPSC from Fibroblasts, Episomal, Male, Control Lines for Genome Editing Services) *Academic Price  0.5 x 10^6 cells/vial 
ASE-9409  Genome Edited iPSCs (KO) PINK1+/- Parkinson's Disease (PD), Monoallelic KO *Academic Price  vial (1 x 10^6) 
ASE-9209  iPS Cells (iPSC from Fibroblasts, Episomal, Female, Control Lines for Genome Editing Services) *Academic Price  0.5 x 10^6 cells/vial 
ASE-9109  iPS Cells (iPSC from Cord Blood Cells CD34+; Male, Master Lines for Neural Differentiation) *Academic Price  1 vial (1 x 10^6) 
ASE-9110  iPS Cells (iPSC from Cord Blood Cells CD34+; Female, Master Lines for Neural Differentiation) *Academic Price  1 vial (1 x 10^6) 
ASE-9502  Genome Edited iPSCs (KI), Safe-Harbor, Neuron Reporter, AAVS-DCX-GFP *Academic Price  1 vial (1 x 10^6) 
ASE-9503  Genome Edited iPSCs (KI) Safe Harbor CAG-GFP-Chr19-Hetero *Academic Price  1 vial (1 x 10^6) 
ASE-9504  Genome Edited iPSCs (KI) Safe Harbor, Ubiquitous Reporter, CAG-GFP-Chr13-Hetero *MTA *Academic Price  1 vial (1 x 10^6) 
ASE-9400  Genome Edited iPSCs (KO) PARK2-/-, Parkinson's Disease (PD), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9401  Genome Edited iPSCs (KO) PARK7-/-, Parkinson's Disease (PD), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9402  Genome Edited iPSCs (KO) PINK1-/- Parkinson's Disease (PD), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9403  Genome Edited iPSCs (KO) LRRK2-/- Parkinson's Disease (PD), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9404  Genome Edited iPSCs (KO) BDNF-/-, Central Nervous System Disease (CNS), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9405  Genome Edited iPSCs (KO) APOE-/-, Alzheimer's Disease (AD), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9406  Genome Edited iPSCs (KO) DISC1-/-, Schizophrenia, Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9407  Genome Edited iPSCs (KO) SOD1-/-, Amyotrophic Lateral Sclerosis (ALS), Biallelic KO *Academic Price  1 vial (1 x 10^6) 
ASE-9408  Genome Edited iPSCs (KO) CNTNAP2-/-, Autism, Biallelic KO *Academic Price  1 vial (1 x 10^6)